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A tool for deterministic and probabilistic sensitivity analysis of epidemiologic studies AgEcon
Orsini, Nicola; Bellocco, Rino; Bottai, Matteo; Wolk, Alicja; Greenland, Sander.
Classification errors, selection bias, and uncontrolled confounders are likely to be present in most epidemiologic studies, but the uncertainty introduced by these types of biases is seldom quantified. The authors present a simple yet easy-to-use Stata command to adjust the relative risk for exposure misclassification, selection bias, and an unmeasured confounder. This command implements both deterministic and probabilistic sensitivity analysis. It allows the user to specify a variety of probability distributions for the bias parameters, which are used to simulate distributions for the bias-adjusted exposure–disease relative risk. We illustrate the command by applying it to a case–control study of occupational resin exposure and lung-cancer deaths. By...
Tipo: Article Palavras-chave: Episens; Episensi; Sensitivity analysis; Unmeasured confounder; Misclassification; Bias; Epidemiology; Research Methods/ Statistical Methods.
Ano: 2008 URL: http://purl.umn.edu/120927
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Confidence intervals for the variance component of random-effects linear models AgEcon
Bottai, Matteo; Orsini, Nicola.
We present the postestimation command xtvc to provide confidence intervals for the variance components of random-effects linear regression models. This command must be used after xtreg with option mle. Confidence intervals are based on the inversion of a score-based test (Bottai 2003).
Tipo: Journal Article Palavras-chave: Xtvc; Variance components; Confidence intervals; Score test; Random-effects linear models; Research Methods/ Statistical Methods.
Ano: 2004 URL: http://purl.umn.edu/116270
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Generalized least squares for trend estimation of summarized dose–response data AgEcon
Orsini, Nicola; Bellocco, Rino; Greenland, Sander.
This paper presents a command, glst, for trend estimation across different exposure levels for either single or multiple summarized case–control, incidence-rate, and cumulative incidence data. This approach is based on constructing an approximate covariance estimate for the log relative risks and estimating a corrected linear trend using generalized least squares. For trend analysis of multiple studies, glst can estimate fixed- and random-effects metaregression models.
Tipo: Journal Article Palavras-chave: Glst; Dose–response data; Generalized least squares; Trend; Meta-analysis; Metaregression; Research Methods/ Statistical Methods.
Ano: 2006 URL: http://purl.umn.edu/117556
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Introduction to game-theory calculations AgEcon
Orsini, Nicola; Rizzuto, Debora; Nante, Nicola.
Game theory can be defined as the study of mathematical models of conflict and cooperation between intelligent and rational decision makers (Myerson 1991). Game-theory concepts apply in economy, sociology, biology, and health care, and whenever the actions of several agents (individuals, groups, or any combination of these) are interdependent. We present a new command gamet to represent the extensive form (game tree) and the strategic form (payoff matrix) of a noncooperative game and to identify the solution of a nonzero and zero-sum game through dominant and dominated strategies, iterated elimination of dominated strategies, and Nash equilibrium in pure and fully mixed strategies. Further, gamet can identify the solution of a zero-sum game through maximin...
Tipo: Journal Article Palavras-chave: Game theory; Nash equilibrium; Payoff matrix; Zero-sum game; Game tree; Research Methods/ Statistical Methods.
Ano: 2005 URL: http://purl.umn.edu/117525
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